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A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis

The genetic component of Immunoglobulin-A (IgA) vasculitis is still far to be elucidated. To increase the current knowledge on the genetic component of this vasculitis we performed the first genome-wide association study (GWAS) on this condition. 308 IgA vasculitis patients and 1,018 healthy control...

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Detalles Bibliográficos
Autores principales: López-Mejías, Raquel, Carmona, F. David, Castañeda, Santos, Genre, Fernanda, Remuzgo-Martínez, Sara, Sevilla-Perez, Belén, Ortego-Centeno, Norberto, Llorca, Javier, Ubilla, Begoña, Mijares, Verónica, Pina, Trinitario, Miranda-Filloy, José A., Navas Parejo, Antonio, de Argila, Diego, Aragües, Maximiliano, Rubio, Esteban, Luque, Manuel León, Blanco-Madrigal, Juan María, Galíndez-Aguirregoikoa, Eva, Jayne, David, Blanco, Ricardo, Martín, Javier, González-Gay, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506002/
https://www.ncbi.nlm.nih.gov/pubmed/28698626
http://dx.doi.org/10.1038/s41598-017-03915-2