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Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells

AIMS/HYPOTHESIS: Endothelial cells (ECs) play an essential role in pancreatic organogenesis. We hypothesise that effective in vitro interactions between human microvascular endothelial cells (HMECs) and human pluripotent stem cells (hPSCs) results in the generation of functional pancreatic beta cell...

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Detalles Bibliográficos
Autores principales: Talavera-Adame, Dodanim, Woolcott, Orison O., Ignatius-Irudayam, Joseph, Arumugaswami, Vaithilingaraja, Geller, David H., Dafoe, Donald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506104/
https://www.ncbi.nlm.nih.gov/pubmed/27567623
http://dx.doi.org/10.1007/s00125-016-4078-1