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Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity

Epigenetic mechanisms have emerged as key players in cancer development which affect cellular states at multiple stages of the disease. During carcinogenesis, alterations in chromatin and DNA methylation resulting from genetic lesions unleash cellular plasticity and favor oncogenic cellular reprogra...

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Detalles Bibliográficos
Autores principales: Wainwright, Elanor N., Scaffidi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506260/
https://www.ncbi.nlm.nih.gov/pubmed/28718414
http://dx.doi.org/10.1016/j.trecan.2017.04.004