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Characterization of retroviral infectivity and superinfection resistance during retrovirus-mediated transduction of mammalian cells

Retroviral vectors including lentiviral vectors are commonly used tools to stably express transgenes or RNA molecules in mammalian cells. Their utilities are roughly divided into two categories, stable overexpression of transgenes and RNA molecules, which requires maximal transduction efficiency, or...

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Detalles Bibliográficos
Autores principales: Liao, J, Wei, Q, Fan, J, Zou, Y, Song, D, Liu, J, Liu, F, Ma, C, Hu, X, Li, L, Yu, Y, Qu, X, Chen, L, Yu, X, Zhang, Z, Zhao, C, Zeng, Z, Zhang, R, Yan, S, Wu, T, Wu, X, Shu, Y, Lei, J, Li, Y, Zhang, W, Wang, J, Reid, R R, Lee, M J, Huang, W, Wolf, J M, He, T-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506371/
https://www.ncbi.nlm.nih.gov/pubmed/28387759
http://dx.doi.org/10.1038/gt.2017.24