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Kallistatin reduces vascular senescence and aging by regulating microRNA‐34a‐SIRT1 pathway

Kallistatin, an endogenous protein, protects against vascular injury by inhibiting oxidative stress and inflammation in hypertensive rats and enhancing the mobility and function of endothelial progenitor cells (EPCs). We aimed to determine the role and mechanism of kallistatin in vascular senescence...

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Detalles Bibliográficos
Autores principales: Guo, Youming, Li, Pengfei, Gao, Lin, Zhang, Jingmei, Yang, Zhirong, Bledsoe, Grant, Chang, Eugene, Chao, Lee, Chao, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506400/
https://www.ncbi.nlm.nih.gov/pubmed/28544111
http://dx.doi.org/10.1111/acel.12615