Inducible knockdown of pregnancy‐associated plasma protein‐A gene expression in adult female mice extends life span

Pregnancy‐associated plasma protein‐A (PAPP‐A) knockout (KO) mice, generated through homologous recombination in embryonic stem cells, have a significantly increased lifespan compared to wild‐type littermates. However, it is unknown whether this longevity advantage would pertain to PAPP‐A gene delet...

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Detalles Bibliográficos
Autores principales: Bale, Laurie K., West, Sally A., Conover, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506424/
https://www.ncbi.nlm.nih.gov/pubmed/28600811
http://dx.doi.org/10.1111/acel.12624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506424/
https://www.ncbi.nlm.nih.gov/pubmed/28600811
http://dx.doi.org/10.1111/acel.12624

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