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Inducible knockdown of pregnancy‐associated plasma protein‐A gene expression in adult female mice extends life span
Pregnancy‐associated plasma protein‐A (PAPP‐A) knockout (KO) mice, generated through homologous recombination in embryonic stem cells, have a significantly increased lifespan compared to wild‐type littermates. However, it is unknown whether this longevity advantage would pertain to PAPP‐A gene delet...
Autores principales: | Bale, Laurie K., West, Sally A., Conover, Cheryl A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506424/ https://www.ncbi.nlm.nih.gov/pubmed/28600811 http://dx.doi.org/10.1111/acel.12624 |
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