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Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging

Skeletal muscle aging is accompanied by loss of muscle mass and strength. Examining changes in myonuclear proteins with age would provide insight into molecular processes which regulate these profound changes in muscle physiology. However, muscle tissue is highly adapted for contraction and thus com...

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Detalles Bibliográficos
Autores principales: Cutler, Alicia A., Dammer, Eric B., Doung, Duc M., Seyfried, Nicholas T., Corbett, Anita H., Pavlath, Grace K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506426/
https://www.ncbi.nlm.nih.gov/pubmed/28544616
http://dx.doi.org/10.1111/acel.12604