Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape

Ideally, disease modeling using patient‐derived induced pluripotent stem cells (iPSCs) enables analysis of disease initiation and progression. This requires any pathological features of the patient cells used for reprogramming to be eliminated during iPSC generation. Hutchinson–Gilford progeria synd...

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Detalles Bibliográficos
Autores principales: Chen, Zhaoyi, Chang, Wing Y., Etheridge, Alton, Strickfaden, Hilmar, Jin, Zhigang, Palidwor, Gareth, Cho, Ji‐Hoon, Wang, Kai, Kwon, Sarah Y., Doré, Carole, Raymond, Angela, Hotta, Akitsu, Ellis, James, Kandel, Rita A., Dilworth, F. Jeffrey, Perkins, Theodore J., Hendzel, Michael J., Galas, David J., Stanford, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506428/
https://www.ncbi.nlm.nih.gov/pubmed/28597562
http://dx.doi.org/10.1111/acel.12621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506428/
https://www.ncbi.nlm.nih.gov/pubmed/28597562
http://dx.doi.org/10.1111/acel.12621

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