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Identification of tissue‐specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics

Caloric restriction (CR) without malnutrition has been shown to retard several aspects of the aging process and to extend lifespan in different species. There is strong interest in the identification of CR mimetics (CRMs), compounds that mimic the beneficial effects of CR on lifespan and healthspan...

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Detalles Bibliográficos
Autores principales: Barger, Jamie L., Vann, James M., Cray, Nicole L., Pugh, Thomas D., Mastaloudis, Angela, Hester, Shelly N., Wood, Steven M., Newton, Michael A., Weindruch, Richard, Prolla, Tomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506434/
https://www.ncbi.nlm.nih.gov/pubmed/28556428
http://dx.doi.org/10.1111/acel.12608