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Deletion of ghrelin prevents aging‐associated obesity and muscle dysfunction without affecting longevity

During aging, decreases in energy expenditure and locomotor activity lead to body weight and fat gain. Aging is also associated with decreases in muscle strength and endurance leading to functional decline. Here, we show that lifelong deletion of ghrelin prevents development of obesity associated wi...

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Detalles Bibliográficos
Autores principales: Guillory, Bobby, Chen, Ji‐an, Patel, Shivam, Luo, Jiaohua, Splenser, Andres, Mody, Avni, Ding, Michael, Baghaie, Shiva, Anderson, Barbara, Iankova, Blaga, Halder, Tripti, Hernandez, Yamileth, Garcia, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506439/
https://www.ncbi.nlm.nih.gov/pubmed/28585250
http://dx.doi.org/10.1111/acel.12618