Enhanced NOLC1 promotes cell senescence and represses hepatocellular carcinoma cell proliferation by disturbing the organization of nucleolus

The nucleolus is a key organelle that is responsible for the synthesis of rRNA and assembly of ribosomal subunits, which is also the center of metabolic control because of the critical role of ribosomes in protein synthesis. Perturbations of rRNA biogenesis are closely related to cell senescence and...

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Detalles Bibliográficos
Autores principales: Yuan, Fuwen, Zhang, Yu, Ma, Liwei, Cheng, Qian, Li, Guodong, Tong, Tanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506443/
https://www.ncbi.nlm.nih.gov/pubmed/28493459
http://dx.doi.org/10.1111/acel.12602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506443/
https://www.ncbi.nlm.nih.gov/pubmed/28493459
http://dx.doi.org/10.1111/acel.12602

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