DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age

Age‐related bone loss in mice results from a decrease in bone formation and an increase in cortical bone resorption. The former is accounted by a decrease in the number of postmitotic osteoblasts which synthesize the bone matrix and is thought to be the consequence of age‐dependent changes in mesenc...

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Detalles Bibliográficos
Autores principales: Kim, Ha‐Neui, Chang, Jianhui, Shao, Lijian, Han, Li, Iyer, Srividhya, Manolagas, Stavros C., O'Brien, Charles A., Jilka, Robert L., Zhou, Daohong, Almeida, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506444/
https://www.ncbi.nlm.nih.gov/pubmed/28401730
http://dx.doi.org/10.1111/acel.12597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506444/
https://www.ncbi.nlm.nih.gov/pubmed/28401730
http://dx.doi.org/10.1111/acel.12597

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