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Increased FNDC5 is associated with insulin resistance in high fat‐fed mice

FNDC5/irisin, has recently been identified as a novel protein that stimulates the “browning” of white adipose by inducing thermogenesis via increased uncoupling protein 1 (UCP1). We tested the hypothesis that high fat diet‐induced prediabetic mice would exhibit increased FNDC5 and this effect would...

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Detalles Bibliográficos
Autores principales: Guilford, Brianne L., Parson, Jake C., Grote, Caleb W., Vick, Stephanie N., Ryals, Janelle M., Wright, Douglas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506519/
https://www.ncbi.nlm.nih.gov/pubmed/28676551
http://dx.doi.org/10.14814/phy2.13319