Comparative assessment of saliva and plasma for drug bioavailability and bioequivalence studies in humans

Aims: To study the pharmacokinetics of selected drugs in plasma and saliva matrixes in healthy human volunteers, and to suggest using non-invasive saliva sampling instead of plasma as a surrogate in bioavailability and bioequivalence (BA/BE) studies. Methods: Four different pilot BA/BE studies were...

Descripción completa

Detalles Bibliográficos
Autor principal: Idkaidek, Nasir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506617/
https://www.ncbi.nlm.nih.gov/pubmed/28725138
http://dx.doi.org/10.1016/j.jsps.2016.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506617/
https://www.ncbi.nlm.nih.gov/pubmed/28725138
http://dx.doi.org/10.1016/j.jsps.2016.10.002

Ejemplares similares