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Comparative assessment of saliva and plasma for drug bioavailability and bioequivalence studies in humans

Aims: To study the pharmacokinetics of selected drugs in plasma and saliva matrixes in healthy human volunteers, and to suggest using non-invasive saliva sampling instead of plasma as a surrogate in bioavailability and bioequivalence (BA/BE) studies. Methods: Four different pilot BA/BE studies were...

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Detalles Bibliográficos
Autor principal:	Idkaidek, Nasir M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506617/ https://www.ncbi.nlm.nih.gov/pubmed/28725138 http://dx.doi.org/10.1016/j.jsps.2016.10.002

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