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Collagen triple helix repeat containing-1 negatively regulated by microRNA-30c promotes cell proliferation and metastasis and indicates poor prognosis in breast cancer

BACKGROUND: Collagen triple helix repeat containing-1 (CTHRC1), which was firstly identified overexpressed in the adventitia and neointima of injured rat arteries, could inhibit collagen expression and increase cell migration. It was then found to be ubiquitously expressed in numerous cell types suc...

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Detalles Bibliográficos
Autores principales: Lai, Yuan-hui, Chen, Jian, Wang, Xiao-ping, Wu, Yan-qing, Peng, Hai-tao, Lin, Xiao-hong, Wang, Wen-jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506643/
https://www.ncbi.nlm.nih.gov/pubmed/28697793
http://dx.doi.org/10.1186/s13046-017-0564-7