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Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells

BACKGROUND: Gram-positive bacteria stimulate Toll-like receptor (TLR) 2 and then activate the pro-inflammatory nuclear factor-kappa B (NF-κB) pathway. As the human ocular surface is heavily colonised by gram-positive cocci bacteria, a balance of activation/repression of NF-κB target genes is essenti...

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Detalles Bibliográficos
Autores principales: Hou, Aihua, Tin, Min Qi, Tong, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506675/
https://www.ncbi.nlm.nih.gov/pubmed/28706958
http://dx.doi.org/10.1186/s40662-017-0082-x