Autophagy mediates cell cycle response by regulating nucleocytoplasmic transport of PAX6 in limbal stem cells under ultraviolet-A stress

Limbal stem cells (LSC) account for homeostasis and regeneration of corneal epithelium. Solar ultraviolet A (UVA) is the major source causing oxidative damage in the ocular surface. Autophagy, a lysosomal degradation mechanism, is essential for physiologic function and stress defense of stem cells....

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Detalles Bibliográficos
Autores principales: Laggner, Maria, Pollreisz, Andreas, Schmidinger, Gerald, Schmidt-Erfurth, Ursula, Chen, Ying-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507275/
https://www.ncbi.nlm.nih.gov/pubmed/28700649
http://dx.doi.org/10.1371/journal.pone.0180868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507275/
https://www.ncbi.nlm.nih.gov/pubmed/28700649
http://dx.doi.org/10.1371/journal.pone.0180868

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