Inflammation dependent mTORC1 signaling interferes with the switch from keratinocyte proliferation to differentiation

Psoriasis is a frequent and often severe inflammatory skin disease, characterized by altered epidermal homeostasis. Since we found previously that Akt/mTOR signaling is hyperactivated in psoriatic skin, we aimed at elucidating the role of aberrant mTORC1 signaling in this disease. We found that unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Buerger, Claudia, Shirsath, Nitesh, Lang, Victoria, Berard, Alina, Diehl, Sandra, Kaufmann, Roland, Boehncke, Wolf-Henning, Wolf, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507280/
https://www.ncbi.nlm.nih.gov/pubmed/28700632
http://dx.doi.org/10.1371/journal.pone.0180853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507280/
https://www.ncbi.nlm.nih.gov/pubmed/28700632
http://dx.doi.org/10.1371/journal.pone.0180853

Ejemplares similares