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Dysregulated CD46 shedding interferes with Th1‐contraction in systemic lupus erythematosus
IFN‐γ‐producing T helper 1 (Th1) cell responses mediate protection against infections but uncontrolled Th1 activity also contributes to a broad range of autoimmune diseases. Autocrine complement activation has recently emerged as key in the induction and contraction of human Th1 immunity: activation...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507296/ https://www.ncbi.nlm.nih.gov/pubmed/28444759 http://dx.doi.org/10.1002/eji.201646822 |