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Dysregulated CD46 shedding interferes with Th1‐contraction in systemic lupus erythematosus

IFN‐γ‐producing T helper 1 (Th1) cell responses mediate protection against infections but uncontrolled Th1 activity also contributes to a broad range of autoimmune diseases. Autocrine complement activation has recently emerged as key in the induction and contraction of human Th1 immunity: activation...

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Detalles Bibliográficos
Autores principales:	Ellinghaus, Ursula, Cortini, Andrea, Pinder, Christopher L., Le Friec, Gaelle, Kemper, Claudia, Vyse, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Immunodeficiencies and autoimmunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507296/ https://www.ncbi.nlm.nih.gov/pubmed/28444759 http://dx.doi.org/10.1002/eji.201646822

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