Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1

Cancer-Associated Fibroblasts (CAFs) are the most prominent stromal cell type in breast tumors. CAFs promote tumor growth and metastasis by multiple mechanisms, including by mediating tumor-promoting inflammation. Immune modulation in the tumor microenvironment plays a central role in determining di...

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Detalles Bibliográficos
Autores principales: Cohen, N, Shani, O, Raz, Y, Sharon, Y, Hoffman, D, Abramovitz, L, Erez, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507301/
https://www.ncbi.nlm.nih.gov/pubmed/28368410
http://dx.doi.org/10.1038/onc.2017.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507301/
https://www.ncbi.nlm.nih.gov/pubmed/28368410
http://dx.doi.org/10.1038/onc.2017.65

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