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Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects

Fatigue is the symptom most commonly reported by long-term cancer survivors and is increasingly recognized as related to skeletal muscle dysfunction. Traditional chemotherapeutic agents can cause acute toxicities including cardiac and skeletal myopathies. To investigate the mechanism by which chemot...

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Detalles Bibliográficos
Autores principales: Crouch, Marie-Laure, Knowels, Gary, Stuppard, Rudolph, Ericson, Nolan G., Bielas, Jason H., Marcinek, David J., Syrjala, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507312/
https://www.ncbi.nlm.nih.gov/pubmed/28700655
http://dx.doi.org/10.1371/journal.pone.0181086