Cargando…
Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects
Fatigue is the symptom most commonly reported by long-term cancer survivors and is increasingly recognized as related to skeletal muscle dysfunction. Traditional chemotherapeutic agents can cause acute toxicities including cardiac and skeletal myopathies. To investigate the mechanism by which chemot...
Autores principales: | Crouch, Marie-Laure, Knowels, Gary, Stuppard, Rudolph, Ericson, Nolan G., Bielas, Jason H., Marcinek, David J., Syrjala, Karen L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507312/ https://www.ncbi.nlm.nih.gov/pubmed/28700655 http://dx.doi.org/10.1371/journal.pone.0181086 |
Ejemplares similares
-
AGED MICE ARE SUSCEPTIBLE TO CARDIAC HYPERTROPHY AFTER 1 WEEK OF CONSUMING A HIGH SUGAR DIET
por: Valencia, Ana P, et al.
Publicado: (2019) -
Elamipretide Improves ADP Sensitivity in Aged Mitochondria by Increasing Uptake through the Adenine Nucleotide Translocator (ANT)
por: Pharaoh, Gavin, et al.
Publicado: (2023) -
Age and Sex as Determinants of Acute Domoic Acid Toxicity in a Mouse Model
por: Hendrix, Alicia M., et al.
Publicado: (2023) -
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)
por: Pharaoh, Gavin, et al.
Publicado: (2023) -
Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits
por: Alexander, Jenolyn F., et al.
Publicado: (2021)