Small-molecule inhibition of pyruvate phosphate dikinase targeting the nucleotide binding site

Pyruvate phosphate dikinase (PPDK) is an essential enzyme of C(4) photosynthesis in plants, catalyzing the ATP-driven conversion of pyruvate to phosphoenolpyruvate (PEP). It is further used by some bacteria and unicellular protists in the reverse, ATP-forming direction. Many weed species use C(4) ph...

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Detalles Bibliográficos
Autores principales: Minges, Alexander, Groth, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507339/
https://www.ncbi.nlm.nih.gov/pubmed/28700696
http://dx.doi.org/10.1371/journal.pone.0181139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507339/
https://www.ncbi.nlm.nih.gov/pubmed/28700696
http://dx.doi.org/10.1371/journal.pone.0181139

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