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Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis

OBJECTIVE: To identify the major infiltrating phagocytes during leptospirosis and examine the killing mechanism used by the host to eliminate Leptospira interrogans. METHODS: Major infiltrating phagocytes in Leptospira-infected C3H/HeJ mice were detected by immunohistochemistry. Chemokines and vascu...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Li, Shi-Jun, Ojcius, David M., Sun, Ai-Hua, Hu, Wei-Lin, Lin, Xu’ai, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507415/
https://www.ncbi.nlm.nih.gov/pubmed/28700741
http://dx.doi.org/10.1371/journal.pone.0181014