Real sequence effects on the search dynamics of transcription factors on DNA

Recent experiments show that transcription factors (TFs) indeed use the facilitated diffusion mechanism to locate their target sequences on DNA in living bacteria cells: TFs alternate between sliding motion along DNA and relocation events through the cytoplasm. From simulations and theoretical analy...

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Detalles Bibliográficos
Autores principales: Bauer, Maximilian, Rasmussen, Emil S., Lomholt, Michael A., Metzler, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507490/
https://www.ncbi.nlm.nih.gov/pubmed/26154484
http://dx.doi.org/10.1038/srep10072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507490/
https://www.ncbi.nlm.nih.gov/pubmed/26154484
http://dx.doi.org/10.1038/srep10072

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