Cargando…

A density-based approach for detecting complexes in weighted PPI networks by semantic similarity

Protein complex detection in PPI networks plays an important role in analyzing biological processes. A new algorithm-DBGPWN-is proposed for predicting complexes in PPI networks. Firstly, a method based on gene ontology is used to measure semantic similarities between interacted proteins, and the sim...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, HongFang, Liu, Jie, Li, JunHuai, Duan, WenCong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507511/
https://www.ncbi.nlm.nih.gov/pubmed/28704455
http://dx.doi.org/10.1371/journal.pone.0180570