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Cerebrospinal fluid matrix metalloproteinase 9 levels, blood-brain barrier permeability, and treatment outcome in tuberculous meningitis

OBJECTIVES: Tuberculous meningitis is characterized by elevated levels of matrix metalloproteinase 9 (MMP9) in the cerebrospinal fluid (CSF). However, it is unclear whether elevated MMP9 levels are associated with poor treatment outcome. We tested the hypothesis that pretreatment MMP9 levels in the...

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Detalles Bibliográficos
Autores principales: Mailankody, Sharada, Dangeti, Gurukiran V., Soundravally, Rajendiran, Joseph, Noyal M., Mandal, Jharna, Dutta, Tarun K., Kadhiravan, Tamilarasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507543/
https://www.ncbi.nlm.nih.gov/pubmed/28704492
http://dx.doi.org/10.1371/journal.pone.0181262