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Essential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions

Parasitic diseases caused by kinetoplastid parasites of the genera Trypanosoma and Leishmania are an urgent public health crisis in the developing world. These closely related species possess a number of multimeric enzymes in highly conserved pathways involved in vital functions, such as redox homeo...

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Detalles Bibliográficos
Autores principales: Wachsmuth, Leah M., Johnson, Meredith G., Gavenonis, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507555/
https://www.ncbi.nlm.nih.gov/pubmed/28662026
http://dx.doi.org/10.1371/journal.pntd.0005720