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Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades

Mitochondrial uncoupling protein 1 (UCP1) is essential for nonshivering thermogenesis in brown adipose tissue and is widely accepted to have played a key thermoregulatory role in small-bodied and neonatal placental mammals that enabled the exploitation of cold environments. We map ucp1 sequences fro...

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Detalles Bibliográficos
Autores principales: Gaudry, Michael J., Jastroch, Martin, Treberg, Jason R., Hofreiter, Michael, Paijmans, Johanna L. A., Starrett, James, Wales, Nathan, Signore, Anthony V., Springer, Mark S., Campbell, Kevin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507634/
https://www.ncbi.nlm.nih.gov/pubmed/28706989
http://dx.doi.org/10.1126/sciadv.1602878