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Detection of an ALK Fusion in Colorectal Carcinoma by Hybrid Capture‐Based Assay of Circulating Tumor DNA

ALK rearrangements have been observed in 0.05%–2.5% of patients with colorectal cancers (CRCs) and are predicted to be oncogenic drivers largely mutually exclusive of KRAS, NRAS, or BRAF alterations. Here we present the case of a patient with metastatic CRC who was treatment naïve at the time of mol...

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Detalles Bibliográficos
Autores principales: Lai, Andrea Z., Schrock, Alexa B., Erlich, Rachel L., Ross, Jeffrey S., Miller, Vincent A., Yakirevich, Evgeny, Ali, Siraj M., Braiteh, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507649/
https://www.ncbi.nlm.nih.gov/pubmed/28507204
http://dx.doi.org/10.1634/theoncologist.2016-0376