α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells

ABSTRACT: Tamoxifen resistance (TamR) is the underlying cause of treatment failure in many breast cancer patients receiving tamoxifen. In order to look for noncytotoxic natural products with the ability to reverse TamR, an extract from strain Streptomyces sp. KIB-H0495 was detected to be active. Sub...

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Detalles Bibliográficos
Autores principales: Yang, Rui-Min, Zhang, Xiu-Lei, Wang, Li, Huang, Jian-Ping, Yang, Jing, Yan, Yi-Jun, Luo, Jian-Ying, Wang, Xiang-Ting, Huang, Sheng-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507810/
https://www.ncbi.nlm.nih.gov/pubmed/28634711
http://dx.doi.org/10.1007/s13659-017-0136-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507810/
https://www.ncbi.nlm.nih.gov/pubmed/28634711
http://dx.doi.org/10.1007/s13659-017-0136-8

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