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α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells
ABSTRACT: Tamoxifen resistance (TamR) is the underlying cause of treatment failure in many breast cancer patients receiving tamoxifen. In order to look for noncytotoxic natural products with the ability to reverse TamR, an extract from strain Streptomyces sp. KIB-H0495 was detected to be active. Sub...
Autores principales: | Yang, Rui-Min, Zhang, Xiu-Lei, Wang, Li, Huang, Jian-Ping, Yang, Jing, Yan, Yi-Jun, Luo, Jian-Ying, Wang, Xiang-Ting, Huang, Sheng-Xiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507810/ https://www.ncbi.nlm.nih.gov/pubmed/28634711 http://dx.doi.org/10.1007/s13659-017-0136-8 |
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