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Role of the Primary Cilia on the Macula Densa and Thick Ascending Limbs in Regulation of Sodium Excretion and Hemodynamics

We investigated the significance of the primary cilia on the macula densa and thick ascending limb (TAL) in regulation of renal hemodynamics, sodium excretion, and blood pressure in this study. A tissue-specific primary cilia knock-out (KO) mouse line was generated by crossing NKCC2-Cre mice with IF...

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Detalles Bibliográficos
Autores principales: Song, Jiangping, Wang, Lei, Fan, Fan, Wei, Jin, Zhang, Jie, Lu, Yan, Fu, Yiling, Wang, Shaohui, Juncos, Luis A., Liu, Ruisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507816/
https://www.ncbi.nlm.nih.gov/pubmed/28607127
http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09584