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PCSK9 and carbohydrate metabolism: A double-edged sword

Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a paramount role in the degradation of low-density lipoprotein (LDL) receptors (LDLR) on the hepatic cells surface and subsequently affects LDL particles catabolism and LDL cholesterol (LDL-c) levels. The anti-PCSK9 monoclonal antibodies le...

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Detalles Bibliográficos
Autores principales: Filippatos, Theodosios D, Filippas-Ntekouan, Sebastian, Pappa, Eleni, Panagiotopoulou, Thalia, Tsimihodimos, Vasilios, Elisaf, Moses S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507827/
https://www.ncbi.nlm.nih.gov/pubmed/28751953
http://dx.doi.org/10.4239/wjd.v8.i7.311