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Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus

Doublecortin X (DCX), known to be essential for neuronal migration and cortical layering in the developing brain, is a 40 kDa microtubule (MT)-associated protein. DCX directly interacts with MTs via its two structured doublecortin (DC) domains, but the dynamics of this association and the possible r...

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Detalles Bibliográficos
Autores principales: Moslehi, Maryam, Ng, Dominic C. H., Bogoyevitch, Marie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507856/
https://www.ncbi.nlm.nih.gov/pubmed/28701724
http://dx.doi.org/10.1038/s41598-017-05340-x