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Calcium-activated SK channels control firing regularity by modulating sodium channel availability in midbrain dopamine neurons

Dopamine neurons in the substantia nigra pars compacta and ventral tegmental area regulate behaviours such as reward-related learning, and motor control. Dysfunction of these neurons is implicated in Schizophrenia, addiction to drugs, and Parkinson’s disease. While some dopamine neurons fire single...

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Detalles Bibliográficos
Autores principales: Iyer, Rajeshwari, Ungless, Mark A., Faisal, Aldo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507868/
https://www.ncbi.nlm.nih.gov/pubmed/28701749
http://dx.doi.org/10.1038/s41598-017-05578-5