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Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating

Hematopoietic ontogeny is characterized by distinct primitive and definitive erythroid lineages. Definitive erythroblasts mature and enucleate extravascularly and form a unique membrane skeleton, composed of spectrin, 4.1R-complex, and ankyrinR-complex components, to survive the vicissitudes of the...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Shan, Delgadillo, Luis F., Cyr, Kathryn H., Kingsley, Paul D., An, Xiuli, McGrath, Kathleen E., Mohandas, Narla, Conboy, John G., Waugh, Richard E., Wan, Jiandi, Palis, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507979/
https://www.ncbi.nlm.nih.gov/pubmed/28701737
http://dx.doi.org/10.1038/s41598-017-05498-4