Bias in recent miRBase annotations potentially associated with RNA quality issues

Although microRNAs are supposed to be stable in-vivo, degradation processes potentially blur our knowledge on the small oligonucleotides. We set to quantify the effect of degradation on microRNAs in mouse to identify causes for distorted microRNAs patterns. In liver, we found 298, 99 and 8 microRNAs...

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Detalles Bibliográficos
Autores principales: Ludwig, Nicole, Becker, Meike, Schumann, Timo, Speer, Timo, Fehlmann, Tobias, Keller, Andreas, Meese, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507985/
https://www.ncbi.nlm.nih.gov/pubmed/28701729
http://dx.doi.org/10.1038/s41598-017-05070-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507985/
https://www.ncbi.nlm.nih.gov/pubmed/28701729
http://dx.doi.org/10.1038/s41598-017-05070-0

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