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Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation

Browning of subcutaneous white fat (iWAT) involves several reprograming events, but the underlying mechanisms are incompletely understood. Here we show that the transcription factor Hlx is selectively expressed in brown adipose tissue (BAT) and iWAT, and is translationally upregulated by β3-adrenerg...

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Detalles Bibliográficos
Autores principales: Huang, Lei, Pan, Dongning, Chen, Qingbo, Zhu, Lihua J., Ou, Jianhong, Wabitsch, Martin, Wang, Yong-Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507986/
https://www.ncbi.nlm.nih.gov/pubmed/28701693
http://dx.doi.org/10.1038/s41467-017-00098-2