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Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation
Browning of subcutaneous white fat (iWAT) involves several reprograming events, but the underlying mechanisms are incompletely understood. Here we show that the transcription factor Hlx is selectively expressed in brown adipose tissue (BAT) and iWAT, and is translationally upregulated by β3-adrenerg...
Autores principales: | Huang, Lei, Pan, Dongning, Chen, Qingbo, Zhu, Lihua J., Ou, Jianhong, Wabitsch, Martin, Wang, Yong-Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507986/ https://www.ncbi.nlm.nih.gov/pubmed/28701693 http://dx.doi.org/10.1038/s41467-017-00098-2 |
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