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Deconvolution of the Response to Bacillus Calmette–Guérin Reveals NF-κB-Induced Cytokines As Autocrine Mediators of Innate Immunity

Bacillus Calmette–Guérin (BCG) is used as a vaccine and diagnostic test for tuberculosis, as well as immunotherapy in the treatment of bladder cancer. While clinically useful, the response to mycobacterial stimulation is complex and the induced protein signature remains poorly defined. We characteri...

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Detalles Bibliográficos
Autores principales: Bisiaux, Aurélie, Boussier, Jeremy, Duffy, Darragh, Quintana-Murci, Lluis, Fontes, Magnus, Albert, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507989/
https://www.ncbi.nlm.nih.gov/pubmed/28751891
http://dx.doi.org/10.3389/fimmu.2017.00796