Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer

Tumor heterogeneity is considered a major cause for therapy resistance in colorectal cancer. Sub-populations of cells with different genetic alterations may exist in spatially distinct areas. Upon therapy, resistant sub-clones may enrich and ultimately lead to disease progression. Although ample dat...

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Detalles Bibliográficos
Autores principales: El-Heliebi, Amin, Kashofer, Karl, Fuchs, Julia, Jahn, Stephan W., Viertler, Christian, Matak, Andrija, Sedlmayr, Peter, Hoefler, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508037/
https://www.ncbi.nlm.nih.gov/pubmed/28321501
http://dx.doi.org/10.1007/s00418-017-1557-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508037/
https://www.ncbi.nlm.nih.gov/pubmed/28321501
http://dx.doi.org/10.1007/s00418-017-1557-5

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