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Increased expression of the microRNA 106b~25 cluster and its host gene MCM7 in corticotroph pituitary adenomas is associated with tumor invasion and Crooke’s cell morphology

PURPOSE: MCM7 (minichromosome maintenance complex component 7), a DNA replication licensing factor, is a host gene for the oncogenic miR-106b~25 cluster. It has been recently revealed as a relevant prognostic biomarker in a variety of cancers, including pituitary adenomas. The purpose of this study...

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Detalles Bibliográficos
Autores principales: Garbicz, Filip, Mehlich, Dawid, Rak, Beata, Sajjad, Emir, Maksymowicz, Maria, Paskal, Wiktor, Zieliński, Grzegorz, Włodarski, Paweł K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508039/
https://www.ncbi.nlm.nih.gov/pubmed/28432562
http://dx.doi.org/10.1007/s11102-017-0805-y