BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells

Mitophagy under hypoxia is an important factor for maintaining and regulating stem cell functions. We previously demonstrated that fatty acid synthase (FASN) induced by hypoxia is a critical lipid metabolic factor determining the therapeutic efficacy of umbilical cord blood-derived human mesenchymal...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Ko, So Hee, Lee, Sei-Jung, Lee, Sang Hun, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508529/
https://www.ncbi.nlm.nih.gov/pubmed/28704726
http://dx.doi.org/10.1016/j.redox.2017.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508529/
https://www.ncbi.nlm.nih.gov/pubmed/28704726
http://dx.doi.org/10.1016/j.redox.2017.07.004

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