Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

The identity of the RNA binding proteins (RBPs) that govern cancer stem cell remains poorly characterized. The MSI2 RBP is a central regulator of translation of cancer stem cell programs. Through proteomics analysis of the MSI2 interacting RBP network and functional shRNA screening, we identified 24...

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Detalles Bibliográficos
Autores principales: Vu, Ly P., Prieto, Camila, Amin, Elianna M., Chhangawala, Sagar, Krivtsov, Andrei, Calvo-Vidal, M. Nieves, Chou, Timothy, Chow, Arthur, Minuesa, Gerard, Park, Sun Mi, Barlowe, Trevor S., Taggart, James, Tivnan, Patrick, Deering, Raquel P., Chu, Lisa P, Kwon, Jeong-Ah, Meydan, Cem, Perales-Paton, Javier, Arshi, Arora, Gönen, Mithat, Famulare, Christopher, Patel, Minal, Paietta, Elisabeth, Tallman, Martin S., Lu, Yuheng, Glass, Jacob, Garret-Bakelman, Francine, Melnick, Ari, Levine, Ross, Al-Shahrour, Fatima, Järås, Marcus, Hacohen, Nir, Hwang, Alexia, Garippa, Ralph, Lengner, Christopher J., Armstrong, Scott A, Cerchietti, Leandro, Cowley, Glenn S, Root, David, Doench, John, Leslie, Christina, Ebert, Benjamin L, Kharas, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508533/
https://www.ncbi.nlm.nih.gov/pubmed/28436985
http://dx.doi.org/10.1038/ng.3854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508533/
https://www.ncbi.nlm.nih.gov/pubmed/28436985
http://dx.doi.org/10.1038/ng.3854

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