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High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
Hundreds of genetically characterized cell lines are available for the discovery of genotype-specific cancer vulnerabilities. However, screening large numbers of compounds against large numbers of cell lines is currently impractical, and such experiments are often difficult to control(1-4). Here, we...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508574/ https://www.ncbi.nlm.nih.gov/pubmed/26928769 http://dx.doi.org/10.1038/nbt.3460 |