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Scaffolding of long read assemblies using long range contact information

BACKGROUND: Long read technologies have revolutionized de novo genome assembly by generating contigs orders of magnitude longer than that of short read assemblies. Although assembly contiguity has increased, it usually does not reconstruct a full chromosome or an arm of the chromosome, resulting in...

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Detalles Bibliográficos
Autores principales: Ghurye, Jay, Pop, Mihai, Koren, Sergey, Bickhart, Derek, Chin, Chen-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508778/
https://www.ncbi.nlm.nih.gov/pubmed/28701198
http://dx.doi.org/10.1186/s12864-017-3879-z